Verstanden

Prof. Dr. Albrecht Stroh

Research Group Leader and Head of the Mainz Animal Imaging Center LIR, Professor Institute of Pathophysiology, University Medical Center Mainz

Kontakt

Leibniz-Institut für Resilienzforschung gGmbH
Hanns-Dieter-Hüsch-Weg 19
55128 Mainz

+49 (0)6131 39-21347
Expertise
General Information
Year of Birth

1974

Current Position

Research Group Leader and Head of the Mainz Animal Imaging Center (MAIC), Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Professor Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

 

University training and degrees
2002 – 2005

Ph.D. studies, Member of Graduate school "Damage cascades in neurological disorders - studies with imaging techniques" at Charité University Medicine Berlin, Germany

1996 – 2001

Studies in Biophysics at the Humboldt University Berlin, degree Dipl. Biophys.

1994 – 1996

Studies in Biology at the Free University Berlin, Germany

 

Advanced academic qualifications
2006

Dr. rer. nat., Experimental Biophysics, summa cum laude, Humboldt University Berlin, Germany (supervisors: C. Zimmer, U. Dirnagl, Charité University Medicine, Berlin, Germany)

2001

Diploma in Biophysics, sehr gut, Humboldt University Berlin, Germany

 

Postgraduate professional career
Since 01/2020

Research Group Leader and Head of the Mainz Animal Imaging Center (MAIC) at the Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Since 01/2018

Tenured Associate Professor (W2) of Molecular Imaging and Optogenetics, Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany

2012 – 2018

Assistant Professor (W1) of Molecular Imaging and Optogenetics, Institute of Microscopic Anatomy and Neurobiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany

Head of Mainz Animal Imaging Center (MAIC), DRZ, Mainz

2007 – 2012

Postdoctoral Scholar at the Institute of Neuroscience, Technical University Munich, Germany, with Arthur Konnerth

2005 – 2007

Postdoctoral Scholar at the Department of Bioengineering, Stanford University, CA, USA, with Karl Deisseroth

 

Other professional activities or honors
2018

Editor, Neuromethods volume 133, SpringerNature Optogenetics: A Roadmap. Neuromethods volume 133

2015

Funding for 9.4 T small animal MRI, DFG Major Research Instrumentation Programme,

2 M EUR

2013

Funding for 2 two-photon microscopes with optogenetics integration, DFG Major Research Instrumentation Programme,

1.54 M EUR

2009

Certificate of Merit for contribution: “Rat fMRI at 17.6 T upon implantation of an optical fiber”, ESMRMB 2009

2005

Kurt-Decker-Award, Annual national award for exceptional research assigned by the German Society for Neuroradiology (DGNR)

2003

Young Investigators Award for exceptional research in life sciences and medicine assigned by the Roland-Ernst-Foundation, Leipzig, Germany

 

Selected Publications

Meyer B, Mann C, Götz M, Gerlicher A, Saase V, Yuen KSL, Aedo-Jury F, Gonzalez-Escamilla G, Stroh A, Kalisch R (2019) Increased neural activity in mesostriatal regions after prefrontal transcranial direct current stimulation and L-DOPA administration. J Neurosci 39(27):5326–5335. doi: 10.1523/JNEUROSCI.3128-18.2019.

>> Link zu Pubmed

Ellwardt E, Pramanik G, Luchtman D, Novkovic T, Jubal ER, Vogt J, Arnoux I, Vogelaar CF, Mandal S, Schmalz M, Barger Z, Ruiz de Azua I, Kuhlmann T, Lutz B, Mittmann T, Bittner S, Zipp F, Stroh A (2018) Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nat Neurosci 21(10):1392−1403.

>> Link zu Pubmed

Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert J J, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. eLife 7:e38744. doi: 10.7554/eLife.38744.

>> Link zu Pubmed

Schwalm M, Schmid F, Wachsmuth L, Fois C, Prouvot P H, Kronfeld A, Backhaus H, Albers F, Faber C, Stroh A (2017) Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves. eLife 6:e27602. doi: 10.7554/eLife.27602.

>> Link zu Pubmed

Yang JW, Prouvot PH, Reyes-Puerta V, Stüttgen MC, Stroh A*, Luhmann HJ* (2017) Optogenetic modulation of a minor fraction of parvalbumin-positive interneurons specifically affects spatiotemporal dynamics of spontaneous and sensory-evoked activity in mouse somatosensory cortex in vivo. Cerebral Cortex 27:5784–5803. *equal contribution

>> Link zu Pubmed

Schmid F, Wachsmuth L, Albers F, Schwalm M, Stroh A*, Faber C* (2017) True and apparent optogenetic BOLD fMRI signals. Magn Reson Med 77(1):126–136. *equal contribution

>> Link zu Pubmed

Schmid F, Wachsmuth L, Schwalm M, Prouvot PH, Jubal ER, Fois C, Pramanik G, Zimmer C, Faber C, Stroh A (2016) Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings. J Cereb Blood Flow Metab 36(11):1885–1900.

>> Link zu Pubmed

Stroh A, Adelsberger H, Groh A, Rühlmann C, Fischer S, Schierloh A, Deisseroth K, Konnerth A (2013) Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo. Neuron 77:1136−1150.

>> Link zu Pubmed

Stroh A, Tsai HC, Wang LP, Zhang F, Kressel J, Aravanis A, Santhanam N, Deisseroth K, Konnerth A, Schneider MB (2011) Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells 29:78−88. (Selected and evaluated by Faculty of 1000)

>> Link zu Pubmed

Stroh A, Zimmer C, Werner N, Gertz K, Weir K, Kronenberg G, Steinbrink J, Mueller S, Sieland K, Dirnagl U, Nickenig G, Endres M (2006) Tracking of systemically injected mononuclear cells in the ischemic brain by MRI. NeuroImage 33:886–897.

Kontakt
Leibniz-Institut für Resilienzforschung (LIR) gGmbH
Wallstraße 7
55122 Mainz
Telefon: +49 (0)6131 39-21347
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