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RG Lieb

Prof. Dr Klaus Lieb

Scientific Director, Director of the Department for Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz


GM. SC. Psych. Jan Broll, researcher, PhD student I Email: jan.broll(at)lir-mainz.de

Dr. Isabella Helmreich, psychoterapist (CBT) I Email: isabella.helmreich(at)lir-mainz.de

M.Sc. Lara Hubenschmid, researcher, PhD student I Email: lara.hubenschmid(at)lir-mainz.de

Saskia Lindner, researcher I Email: lindners(at)uni-mainz.de

Jun.-Prof. Dr. Sarah Schäfer, researcher, psychotherapist (CBT) | Email: sarah.schaefer(at)lir-mainz.de

Dipl.-Psych. Jutta Stoffers-Winterling, researcher, psychotherapist | Email: jutta.winterling(at)lir-mainz.de

M. Sc. Psych. Lea Thomas, researcher, PhD student | Email: lea.thomas(at)lir-mainz.de

Research group description

The research group focuses on the following topics:

1) Based on methods of the Cochrane Collaboration, the research group performs systematic reviews and meta-analyses as well as living evidence syntheses on resilience mechanisms and resilience-promoting interventions. Thereby, the research group offers a knowledge base for LIR staff and external scientists.

2) The research group examines trajectories of resilience and mental distress in representative samples and in specific populations and identifies risk and protective factors.

3) The research group studies the implementation of resilience-promoting interventions in the general population and in specific risk groups by monitoring and evaluating intervention effects in everyday life.

Current research projects
  • 1) Systematic reviews on:
  • Trajectories of mental health in face of stress (e.g., COVID-19 pandemic)
  • Resilience factors as predictors of these trajectories
  • Resilience- and health-promoting interventions in the context of different stressors
  • Changes in responses to stress over the lifespan with a special focus on older age
  • 2) Development of psychotherapeutic interventions to promote resilience with a focus on programs provided in group formats and online
  • 3) Optimizing the assessment of resilience (factors) using advances in the field of Machine Learning
  • 4) Optimizing evidence syntheses by implementing new methods of search and data analysis
External cooperation partners
  • Prof. Dr. Iris Pigeot, Leibniz Institute for Prevention Research and Epidemiology, Bremen, Germany
  • Prof. Dr. Harald Binder, Albrecht Ludwigs University of Freiburg, Germany
  • Prof. Dr Alexandra Busch, Römisch-Germanisches Zentralmuseum (RGZM), Leibniz Research Institute for Archaeology, Mainz, Germany
  • Dr. Anita Chasiotis and Dr. Marlene Stoll, Leibniz Institute for Psychology, Trier, Germany
  • Prof. Dr. Andrea Chmitorz, Esslingen University of Applied Sciences, Germany
  • Prof. Dr. Pim Cuijpers, University of Amsterdam, Netherlands
  • Prof. Dr. Peter Falkai, Ludwig Maximilian University of Munich, Germany
  • Dr. Maria Melchior, Institut national de la santé et de la recherche médicale, Paris, Frankreich
  • Prof. Dr. Jörg Meerpohl, Cochrane Germany Foundation, Freiburg
  • Prof. Dr. Helen Morrison, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany
  • Prof. Dr. Norbert Paul, Institute for History, Philosophy and Ethics of Medicine, Mainz, Germany
  • PD Dr. Dorota Reis, Saarland University, Saarbrücken, Germany
  • Prof. Dr. Marit Sijbrandij, University of Amsterdam, Netherlands
  • Prof. Dr. Ole Jakob Storebø, University of Southern Denmark, Odense, Denmark
  • Prof. Dr. Rolf van Dick, Social Psychology, Goethe University Frankfurt, Germany
  • Prof. Dr. Viola Priesemann, Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany
  • BMBF (German Federal Ministry of Education and Research)
  • BMG (German Federal Ministry of Health)
  • DFG (German Research Foundation)
  • European Union
  • Innovation Fund by the Joint Federal Committee
  • Leibniz Association (Cooperative Exellence)
  • Ministry of Science and Health Rhineland Palatinate
Key Publications

Schäfer, S. K., von Boros, L., Schaubruch, L. M., Kunzler, A. M., Lindner, S., Koehler, F., Werner, T., Zappalà, F., Helmreich, I., Wessa, M., Lieb, K., & Tüscher, O. (2024). Digital interventions to promote psychological resilience: a systematic review and meta-analysis. NPJ digital medicine, 7(1), 30. https://doi.org/10.1038/s41746-024-01017-8

>> Link to Pubmed

Kunzler AM, Lindner S, Röthke N, Schäfer SK, Metzendorf MI, Sachkova A, Müller-Eberstein R, Klinger C, Burns J, Coenen M, Lieb K (2023). Mental Health Impact of Early Stages of the COVID-19 Pandemic on Individuals with Pre-Existing Mental Disorders: A Systematic Review of Longitudinal Research. Int J Environ Res Public Health 20(2):948

>> Link to Pubmed

Schäfer, S. K., Thomas, L. M., Lindner, S., & Lieb, K. (2023). World Health Organization's low-intensity psychosocial interventions: a systematic review and meta-analysis of the effects of Problem Management Plus and Step-by-Step. World psychiatry : official journal of the World Psychiatric Association (WPA), 22(3), 449–462. https://doi.org/10.1002/wps.21129

>> Link to Pubmed

Schäfer SK, Kunzler AM, Kalisch R, Tüscher O, Lieb K (2022). Trajectories of resilience and mental distress to global major disruptions. Trends Cogn Sci 26(12):1171-1189. doi: 10.1016/j.tics.2022.09.017

>> Link to Pubmed

Stoll M, Kerwer M, Lieb K, Chasiotis A (2022). Plain language summaries: A systematic review of theory, guidelines and empirical research. PLoS One 17(6):e0268789. doi: 10.1371/journal.pone.0268789

>> Link to Pubmed

Bohus M, Stoffers-Winterling J, Sharp C, Krause-Utz A, Schmahl C, Lieb K (2021). Borderline personality disorder. Lancet 398(10310):1528-1540.

>> Link to Pubmed

Kunzler AM, Röthke N, Günthner L, et al. (2021). Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic: systematic review and meta-analyses. Global Health 17(1):34. doi: 10.1186/s12992-021-00670-y

>> Link to Pubmed

Chmitorz A, Neumann RJ, Kollmann B, Ahrens KF, Öhlschläger S, Goldbach N, Weichert D, Schick A, Lutz B, Plichta MM, Fiebach CJ, Wessa M, Kalisch R, Tüscher O, Lieb K, Reif A (2020) Longitudinal determination of resilience in humans to identify mechanisms of resilience to modern-life stressors: the longitudinal resilience assessment (LORA) study. Eur Arch Psychiatry Clin Neurosci doi: 10.1007/s00406-020-01159-2.

>> Link to Pubmed

Kunzler AM, Helmreich I, Chmitorz A, König J, Binder H, Wessa M, Lieb K (2020) Psychological interventions to foster resilience in healthcare professionals. Cochrane Database Syst Rev 5;7:CD012527. doi: 10.1002/14651858.CD012527.pub2.

>> Link to Pubmed

Kunzler AM, Helmreich I, König J, Chmitorz A, Wessa M, Binder H, Lieb K (2020) Psychological interventions to foster resilience in healthcare students.  Cochrane Database Syst Rev 20;7(7):CD013684. doi: 10.1002/14651858.CD013684.

>> Link to Pubmed

Stoll M, Mancini A, Hubenschmid L, Dreimüller N, König J, Cuijpers P, Barth J, Lieb K (2020) Discrepancies from registered protocols and spin occurred frequently in randomized psychotherapy trials-A meta-epidemiologic study. J Clin Epidemiol 128:49-56.

>> Link to Pubmed

Bagusat C, Kunzler A, Schlecht J, Franke AG, Chmitorz A, Lieb K (2018) Pharmacological neuroenhancement and the ability to recover from stress – a representative cross-sectional survey among the German population. Substance Abuse Treatment, Prevention, and Policy 13(1)37. doi: 10.1186/s13011-018-0174-1

>> Link to article

Chmitorz A*, Kunzler A*, Helmreich I, Tüscher O, Kalisch R, Kubiak T, Wessa M, Lieb K (2018) Intervention studies to foster resilience – a systematic review and proposal for a resilience framework in future intervention studies. Clin Psychol Rev 59:78-100. *Equal contr.

>> Link to Pubmed

Kalisch R, Baker DG, Basten U, Boks MP, Bonanno GA, Brummelman E, Chmitorz A, Fernàndez G, Fiebach CJ, Galatzer-Levy I, Geuze E, Groppa S, Helmreich I, Hendler T, Hermans EJ, Jovanovic T, Kubiak T, Lieb K, Lutz B, Müller MB, Murray RJ, Nievergelt CM, Reif A, Roelofs K, Rutten BPF, Sander D, Schick A, Tüscher O, Diest IV, Harmelen AV, Veer IM, Vermetten E, Vinkers CH, Wager TD, Walter H, Wessa M, Wibral M, Kleim B (2017). The resilience framework as a strategy to combat stress-related disorders. Nat Hum Behav 1(11):784-790. doi: 10.1038/s41562-017-0200-8

>> Link to Pubmed
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