ASSOC. RG Tüscher
Lead:
Prof. Dr Oliver Tüscher
Professor for Mental Health and Resilience in the Old Age University Medical Center of the Johannes Gutenberg-University Mainz
Merve Ilhan, PhD student I Email: merve.ilhan.ext@lir-mainz.de
Dr Bianca Kollmann, Postdoc I Email: bianca.kollmann.ext@lir-mainz.de
Edoardo Pinzuti, PhD student I Email: edoardo.pinzuti@lir-mainz.de
Nicolas Ruffini, PhD student I Email: nicolas.ruffini@lir-mainz.de
Dr Alexandra Sebastian, Postdoc I Email: alexandra.sebastian@lir-mainz.de
Our research group uses modern methods of cognitive behavioural research (behavioural tests and ambulatory assessments) and neurophysiology (fMRI, DTI/VBM, EEG/fMRI, EEG, MEG, EEG/MEG, PET, and imaging genetics) to understand neurocognitive mechanisms of mental resilience of stress-related diseases. Thematic focuses are the systematic study of self-control as a resilience mechanism, in particular the cognitive domains of emotion regulation (ER), impulse control (IC), attention (AC), and social interaction, as well as the translational mechanisms of stress vaccination, taking into account interindividual differences and age processes. Neuronally, hypotheses on oscillatory mechanisms and differences in network excitability on individual resilience are investigated.
- Translational mechanisms of stress vaccination as resilience mechanism
- Mechanisms of emotional interference control
- Mechanisms of proactive interference control - Method development
- Neuronal mechanisms of the brain-wide resting networks in humans
- Development of instruments for dynamic systems analysis in resilience research (IDSAIR)
- Prof. Dr Michael Wibral, Campus Institute for Dynamics of Biological Networks, Georg August University Göttingen
- Prof. Dr Dr. Henrik Walter, Psychiatrie, Humboldt University, Charité, Berlin
- Prof. Dr Birte Forstmann, University of Amsterdam, the Netherlands
- Prof. Dr David Silbersweig, Brigham & Woman's Hospital, Harvard University, Boston, USA
- German Research Foundation (DFG)
- Boehringer Ingelheim Foundation
- MWWK
Mey LK, Wenzel M, Morello K, Rowland Z, Kubiak T, Tüscher O (2023) Be Kind to Yourself: the Implications of Momentary Self-Compassion for Affective Dynamics and Well-Being in Daily Life. Mindfulness 7:1-15
>> Link to PubmedPinzuti E, Wollstadt P, Tüscher O, Wibral M (2023) Information theoretic evidence for layer- and frequency-specific changes in cortical information processing under anesthesia. PLoS Comput Biol. 19(1):e1010380
>> Link to PubmedAhrens KF, Neumann RJ, von Werthern NM, Kranz TM, Kollmann B, Mattes B, Puhlmann LMC, Weichert D, Lutz B, Basten U, Fiebach CJ, Wessa M, Kalisch R, Lieb K, Chiocchetti AG*, Tüscher O*, Reif A*, Plichta MM* (2022) Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown. Transl Psychiatry. 2022 Sep 21;12(1):396. doi: 10.1038/s41398-022-02165-9. (*shared last authors)
>> Link to PubmedIlhan-Bayrakcı M, Cabral-Calderin Y, Bergmann TO, Tüscher O, Stroh A (2022) Individual Slow Wave Events Give Rise to Macroscopic fMRI Signatures and Drive the Strength of the BOLD Signal in Human Resting-State EEG-fMRI Recordings. Cereb Cortex. 2022 Oct 20;32(21):4782-4796. doi: 10.1093/cercor/bhab516. Epub 2022 Jan 30
>> Link to PubmedKöber G, Pooseh S, Engen H, Chmitorz A, Kampa M, Schick A, Sebastian A, Tüscher O, Wessa M, Yuen KSL, Walter H, Kalisch R, Timmer J, Binder H (2022) Individualizing deep dynamic models for psychological resilience data. Sci Rep. 2022 May 16;12(1):8061. doi: 10.1038/s41598-022-11650-6
>> Link to PubmedRiedel D, Fellerhoff T, Mierau A, Strüder H, Wolf D, Fischer F, Fellgiebel A, Tüscher O, Kollmann B, Knaepen K (2022) The impact of aging on interhemispheric transfer time and respective sex differences. Aging Brain 2022 Apr 4;2:100040. doi: 10.1016/j.nbas.2022.100040
>> Link to PubmedAhrens KF, Neumann RJ, Kollmann B, Brokelmann J, von Werthern NM, Malyshau A, Weichert D, Lutz B, Fiebach CJ, Wessa M, Kalisch R, Plichta MM, Lieb K, Tüscher O, Reif A (2021) Impact of COVID-19 lockdown on mental health in Germany: longitudinal observation of different mental health trajectories and protective factors. Transl Psychiatry. 2021 Jul 17;11(1):392. doi: 10.1038/s41398-021-01508-2
>> Link to PubmedRiepenhausen A, Veer IM, Wackerhagen C, Reppmann ZC, Köber G, Ayuso-Mateos JL, Bögemann SA, Corrao G, Felez-Nobrega M, Abad JMH, Hermans E, van Leeuwen J, Lieb K, Lorant V, Mary-Krause M, Mediavilla R, Melchior M, Mittendorfer-Rutz E, Compagnoni MM, Pan KY, Puhlmann L, Roelofs K, Sijbrandij M, Smith P, Tüscher O, Witteveen A, Zerban M, Kalisch R, Kröger H, Walter H (2022) Coping with COVID: risk and resilience factors for mental health in a German representative panel study. Psychol Med. 2022 Mar 1;1-11. doi: 10.1017/S0033291722000563
>> Link to PubmedSchäfer SK, Kunzler AM, Kalisch R, Tüscher O, Lieb K (2022) Trajectories of resilience and mental distress to global major disruptions. Trends Cogn Sci. 2022 Oct 24:S1364-6613(22)00238-8. doi: 10.1016/j.tics.2022.09.017. Online ahead of print
>> Link to PubmedWenzel, M, Rowland, Z, Mey, LK, Kurth, K, Tüscher, O, & Kubiak, T (2022) Variability in negative affect is an important feature of neuroticism above mean negative affect once measurement issues are accounted for. European Journal of Personality, 0(0). /10.1177/08902070221089139
>> Link to articleAhrens KF, Neumann RJ, Kollmann B, Brokelmann J, von Werthern NM, Malyshau A, Weichert D, Lutz B, Fiebach CJ, Wessa M, Kalisch R, Plichta MM, Lieb K, Tüscher O, Reif A (2021) Impact of COVID-19 lockdown on mental health in Germany: longitudinal observation of different mental health trajectories and protective factors. Transl Psychiatry. 2021 Jul 17;11(1):392. doi: 10.1038/s41398-021-01508-2. * shared last authors
>> Link to PubmedAhrens KF, Neumann RJ, Kollmann B, Plichta MM, Lieb K, Tüscher O, Reif A (2021) Differential impact of COVID-related lockdown on mental health in Germany. World Psychiatry 20(1):140-141.
>> Link to PubmedFaraza S, Waldenmaier J, Dyrba M, Wolf D, Fischer FU, Knaepen K, Kollmann B, Tüscher O, Binder H, Mierau A, Riedel D, Fellgiebel A, Teipel S (2021) Dorsolateral Prefrontal Functional Connectivity Predicts Working Memory Training Gains. Front Aging Neurosci. 2021 Mar 1;13:592261. doi: 10.3389/fnagi.2021.592261. eCollection 2021
>> Link to PubmedFischer FU, Wolf D, Tüscher O, Fellgiebel A (2021) Alzheimer’s Disease Neuroimaging Initiative. Structural Network Efficiency Predicts Resilience to Cognitive Decline in Elderly at Risk for Alzheimer's Disease. Front Aging Neurosci 13:637002.
>> Link to PubmedKalisch R, Köber G, Binder H, Ahrens KF, Basten U, Chmitorz A, Choi KW, Fiebach CJ, Goldbach N, Neumann RJ, Kampa M, Kollmann B, Lieb K, Plichta MM, Reif A, Schick A, Sebastian A, Walter H, Wessa M, Yuen KSL, Tüscher O, Engen H (2021) The Frequent Stressor and Mental Health Monitoring-Paradigm: A Proposal for the Operationalization and Measurement of Resilience and the Identification of Resilience Processes in Longitudinal Observational Studies. Front Psychol. 12:710493. doi: 10.3389/fpsyg.2021.710493
>> Link to PubmedPfeifer P, Sebastian A, Buchholz HG, Kaller CP, Gründer G, Fehr C, Schreckenberger M, Tüscher O (2021) Prefrontal and striatal dopamine D 2/D 3 receptors correlate with fMRI BOLD activation during stopping. Brain Imaging Behav. doi: 10.1007/s11682-021-00491-y
>> Link to PubmedSchaum M, Pinzuti E, Sebastian A, Lieb K, Fries P, Mobascher A, Jung P, Wibral M*, Tüscher O* (2021) Right inferior frontal gyrus implements motor inhibitory control via beta-band oscillations in humans. Elife. 2021 Mar 23;10:e61679. doi: 10.7554/eLife.61679. (*equally contributing last authors)
>> Link to PubmedVeer IM, Riepenhausen A, Zerban M, Wackerhagen C, Puhlmann LMC, Engen H, Köber G, Bögemann SA, Weermeijer J, Uściłko A, Mor N, Marciniak MA, Askelund AD, Al-Kamel A, Ayash S, Barsuola G, Bartkute-Norkuniene V, Battaglia S, Bobko Y, Bölte S, Cardone P, Chvojková E, Damnjanović K, De Calheiros Velozo J, de Thurah L, Deza-Araujo YI, Dimitrov A, Farkas K, Feller C, Gazea M, Gilan D, Gnjidić V, Hajduk M, Hiekkaranta AP, Hofgaard LS, Ilen L, Kasanova Z, Khanpour M, Lau BHP, Lenferink DB, Lindhardt TB, Magas DÁ, Mituniewicz J, Moreno-López L, Muzychka S, Ntafouli M, O'Leary A, Paparella I, Põldver N, Rintala A, Robak N, Rosická AM, Røysamb E, Sadeghi S, Schneider M, Siugzdaite R, Stantić M, Teixeira A, Todorovic A, Wan WWN, van Dick R, Lieb K, Kleim B, Hermans EJ, Kobylińska D, Hendler T, Binder H, Myin-Germeys I, van Leeuwen JMC, Tüscher O, Yuen KSL, Walter H, Kalisch R (2021) Psycho-social factors associated with mental resilience in the Corona lockdown. Transl Psychiatry. 2021 Jan; 11(1):67. doi: 10.1038/s41398-020-01150-4. PMID: 33479211
>> Link to Pubmed