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Prof. Dr Oliver Tüscher

Professor for Mental Health and Resilience in the Old Age University Medical Center of the Johannes Gutenberg-University Mainz

Contact

Leibniz-Institut für Resilienzforschung gGmbH
Untere Zahlbacher Straße 8
55131 Mainz

+49 (0)6131 17-7363
General Information
Year of Birth

1971

Current Position

Research Group Leader and Head of Clinical Investigation Center (CIC), Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Professor and Vice-Chair, Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

University training and degrees
10/1992 – 09/1995

Medical School, University of Bochum, Germany

10/1995 – 11/2000

Medical School, University of Heidelberg, Germany

 

Advanced academic qualifications
12/2011

Habilitation for Neurology: “Neurobehavioral mechanisms of emotion processing” University of Freiburg, Germany (supervisor: Prof. C. Weiller)

03/1996 – 03/1999

Graduate program in Molecular and Cellular Neurobiology, equivalent to American M.D./Ph.D. programs, Prof. Dr. W. B. Huttner, Department of Neurobiology, University of Heidelberg, Germany, graduated 02/2002 with Dr. med.

 

Postgraduate professional career
Since 01/2020

Research Group Leader and Head of the Clinical Investigation Center (CIC) at the Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Since 01/2018

Research Group Leader and Head of the Clinical Investigation Center (CIC) at the German Resilience Center (DRZ) Mainz, Germany        

Since 08/2016

W2-Professor of Clinical Resilience Research at the Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz and the German Resilience Center (DRZ) Mainz

Since 02/2015

Vice-chair, Dept. of Psychiatry, University Medical Center of the Johannes Gutenberg University Mainz, Germany

Since 07/2014

Director, Clinical Investigation Center (CIC), DRZ Mainz, Germany

Since 08/2013

Attending in Psychiatry and Psychotherapy

07/2013

Board certification for Psychiatry and Psychotherapy

Since 2012

Director, Center for Clinical Trials on Mental Disorders

Since 2010

Lab head, Emotion Regulation and Impulse Control Imaging Group (ERIC)

10/2010

Board certification for Neurology

04/2010 – to date

Residency, Dept. of Psychiatry, Prof. Dr. K. Lieb, University Medical Center of the Johannes Gutenberg University Mainz, Germany

07/2009 – 10/2010

Residency, Dept. of Psychiatry, Prof. Dr. M. Berger, University of Freiburg, Germany

04/2006 – 10/2010

Head, Emotion Regulation and Impulse Control Imaging Group (ERIC) at the Freiburg Brain Imaging, University of Freiburg, Germany

04/2006 – 06/2009

Residency, Dept. of Neurology, Prof. Dr. C. Weiller, University of Freiburg, Germany

02/2003 – 03/2006

Postdoc and supervised consultant service Div. of Neuropsychiatry, Department of Psychiatry, Prof. Dr. D. Silbersweig, Weill Medical College of Cornell University, New York, NY, USA

04/2001 – 01/2003

Residency (22 months), Departement of Neurology, Prof. Dr. C. Weiller, UKE, University of Hamburg, Germany

 

Other professional activities or honors
01/2019

Secondo loco appointment listing for W3-Prof. (Chair), Univ. Oldenburg

04/2018 – 03/2022

EU2020-777084 “DynaMORE” personalised in-silico model of mental health in the face of adversity, e.g., stress resilience, Work package leader

06/2018

Quarto loco appointment listing for W3-Prof. (Chair), Univ. Lübeck

07/2016 – 06/2020

DFG-CRC 1193 Neurobiology of resilience PI SP C04 with M. Wibral

02/2016

Secondo loco appointment listing for W2-Prof. Psychiatry, Univ. of Würzburg

07/2015 – 06/2019

PI (Functional Imaging) BMBF-Collaborative Research Project Normal aging: „Transfer of cognitive training gains in cognitively healthy aging“

07/2013 – 06/2016

Landesförderung Stiftung Rheinland-Pfalz für Innovation: „Mainzer Resilienz-Projekt (MARP)“ Kalisch, Lieb, Nitsch, Zipp, Mobascher, Tüscher

05/2000

DAAD-Stipend IAS-Programm

03/1996 – 03/1999

DFG-Stipend Graduiertenkolleg Molekulare und zelluläre Neurobiologie

11/2000

Studienstiftung des deutschen Volkes

 

Selected Publications

Ahrens KF, Neumann RJ, Kollmann B, Plichta MM, Lieb K*, Tüscher O*, Reif A* (in press). Differential impact of COVID-related lockdown on mental health in Germany, Letter to the editor (peer-reviewed, original data). World Psychiat. (*shared last authors).

Maier S, Schneider K, Stark C, Zeeck A, Tebartz van Elst L, Holovics L, Hartmann A, Lahmann C, Domschke K, Nickel K, Feige B, Glauche V, Fleischhaker C, Tüscher O*, Joos A* (2019). Fear network unresponsiveness in women with Anorexia Nervosa. Psychother Psychosom 88(4):238-240. doi: 10.1159/000495367. (*equal contribution).

Gerlicher AVM, Tüscher O, Kalisch (2018) Dopamine-dependent prefrontal reactivations explain long-term benefit of fear extinction. Nat Commun 9(1):4294. doi: 10.1038/s41467-018-06785-y. Erratum in: Nat Commun 2019 10(1):471.

>> Link to Pubmed

Sebastian A, Rössler K, Wibral M, Mobascher A, Lieb K, Jung P, Tüscher O (2017) Neural architecture of selective stopping strategies: distinct brain activity patterns are associated with attentional capture but not with outright stopping. J Neurosci 37(40):9785–9794.

>> Link to Pubmed

Sebastian A, Jung P, Neuhoff J, Wibral M, Fox PT, Lieb K, Fries P, Eickhoff SB, Tüscher O*, Mobascher A* (2016) Dissociable attentional and inhibitory networks of dorsal and ventral areas of the right inferior frontal cortex: a combined task-specific and coordinate-based meta-analytic fMRI study. Brain Struct Funct 221(3):1635–1651. *equal contribution

>> Link to Pubmed

Kalisch R, Müller MB, Tüscher O (2015) A conceptual framework for the neurobiological study of resilience. Behav Brain Sci 38:e92. doi: 10.1017/S0140525X1400082X.

>> Link to Pubmed

Endres K, Fahrenholz F, Lotz J, Hiemke C, Teipel S, Lieb K, Tüscher O*, Fellgiebel A* (2014) Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin. Neurology 83:1930–1935. *equal contribution

>> Link to Pubmed

Stahl C, Voss A, Schmitz F, Nuszbaum M, Tüscher O, Lieb K, Klauer KC (2014) Behavioral components of impulsivity. J Exp Psychol Gen 143:850–886.

>> Link to Pubmed

Maier SJ, Szalkowski A, Kamphausen S, Feige B, Perlov E, Kalisch R, Jacob GA, Philipsen A, Tüscher O*, van Elst LT* (2014) Altered cingulate and amygdala response towards threat and safe cues in attention deficit hyperactivity disorder. Psychol Med 44:85–98. *equal contribution

>> Link to Pubmed

Sebastian A, Pohl MF, Klöppel S, Feige B, Lange T, Stahl C, Voss A, Klauer KC, Lieb K, Tüscher O (2013) Disentangling common and specific neural subprocesses of response inhibition. Neuroimage 64:601–615.

>> Link to Pubmed

Hellwig S, Amtage F, Kreft A, Buchert R, Winz OH, Vach W, Spehl TS, Rijntjes M, Hellwig B, Weiller C, Winkler C, Weber WA, Tüscher O, Meyer PT (2012) [¹⁸F]FDG-PET is superior to [¹²³I]IBZM-SPECT for the differential diagnosis of parkinsonism. Neurology 79:1314–1322.

>> Link to Pubmed

Silbersweig D, Clarkin JF, Goldstein M, Kernberg OF, Tüscher O, Levy KN, Brendel G, Pan H, Beutel M, Pavony MT, Epstein J, Lenzenweger MF, Thomas KM, Posner MI, Stern E (2007) Failure of frontolimbic inhibitory function in the context of negative emotion in borderline personality disorder. Am J Psychiatry 164:1832–1841.

>> Link to Pubmed

Ahrens KF, Neumann RJ, Kollmann B, Brokelmann J, von Werthern NM, Malyshau A, Weichert D, Lutz B, Fiebach CJ, Wessa M, Kalisch R, Plichta MM, Lieb K, Tüscher O, Reif A (2021). Impact of COVID-19 lockdown on mental health in Germany: longitudinal observation of different mental health trajectories and protective factors. Transl Psychiatry. 2021 Jul 17;11(1):392. doi: 10.1038/s41398-021-01508-2

>> Link to Pubmed

Ahrens KF, Neumann RJ, Kollmann B, Plichta MM, Lieb K, Tüscher O, Reif A (2021). Differential impact of COVID-related lockdown on mental health in Germany. World Psychiatry. 20(1):140-141. doi: 10.1002/wps.20830 | IF 79,6

>> Link to Pubmed

Fischer FU, Wolf D, Tüscher O, Fellgiebel A (2021). Alzheimer’s Disease Neuroimaging Initiative. Structural Network Efficiency Predicts Resilience to Cognitive Decline in Elderly at Risk for Alzheimer's Disease. Front Aging Neurosci. 2021 Feb. 13:637002. doi: 10.3389/fnagi.2021.637002. eCollection 2021 | IF 5,8

>> Link to Pubmed

Pfeifer P, Sebastian A, Buchholz HG, Kaller CP, Gründer G, Fehr C, Schreckenberger M, Tüscher O (2021). Prefrontal and striatal dopamine D 2/D 3 receptors correlate with fMRI BOLD activation during stopping. Brain Imaging Behav. doi: 10.1007/s11682-021-00491-y. | IF 4,0

>> Link to Pubmed

Schaum M, Pinzuti E, Sebastian A, Lieb K, Fries P, Mobascher A, Jung P, Wibral M*, Tüscher O*(2021). Right inferior frontal gyrus implements motor inhibitory control via beta-band oscillations in humans. Elife. 2021 Mar 23;10:e61679. doi: 10.7554/eLife.61679. *equally contributing last authors.

>> Link to Pubmed

Riedel D, Fellerhoff T, Mierau A, Strüder H, Wolf D, Fischer F, Fellgiebel A, Tüscher O, Kollmann B, Knaepen K (2022). The impact of aging on interhemispheric transfer time and respective sex differences. Aging Brain 2022 Apr 4;2:100040. doi: 10.1016/j.nbas.2022.100040

>> Link to article
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