Prof. Dr Raffael Kalisch
Research Group Leader LIR, Director of Neuroimaging Center Mainz, Professor of Human Neuroimaging
Leibniz-Institut für Resilienzforschung gGmbH
Langenbeckstraße 1
55131 Mainz
1972
Research Group Leader, Leibniz Institute for Resilience Research (LIR), Mainz, Germany
Professor of Human Neuroimaging and Director of Neuroimaging Center (NIC), Mainz, University Medical Center of the Johannes Gutenberg-University Mainz, Germany
Human Biology (Theoretical Medicine), University of Marburg, Germany; Dipl. Hum. biol. (supervisor: A. Triller, Ecole Normale Supérieure, Paris)
Maitrise de Biologie cellulaire et Physiologie, Université Paris VII, Paris, France; guest student without degree
Human Biology (Theoretical Medicine), University of Marburg, Germany
Dr. rer. nat.: Biology, Ludwig Maximilian University Munich, Germany (supervisor: R. Landgraf, Max Planck Institute for Psychiatry, Munich)
Research Group Leader at the Leibniz Institute for Resilience Research (LIR), Mainz, Germany
Professor for Human Neuroimaging (W3) and Director, Neuroimaging Center Mainz (NIC), University Medical Center of the Johannes Gutenberg University Mainz, Germany
Research Group Leader at the German Resilience Center (DRZ) Mainz, Germany
Professor for Human Neuroimaging (W2) and Director, Neuroimaging Center Mainz (NIC), University Medical Center of the Johannes Gutenberg University Mainz, Germany
DFG Emmy Noether Research Group Leader, Institute for Systems Neuroscience, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany
Research Group Leader, Institute for Systems Neuroscience, UKE, Hamburg, Germany
Postdoctoral researcher, Institute for Systems Neuroscience, UKE, Hamburg, Germany (supervisor: C. Büchel)
Postdoctoral researcher, Wellcome Department of Imaging Neuroscience, University College London, United Kingdom (supervisor: R. Dolan)
Postdoctoral researcher, NMR study group, Max Planck Institute for Psychiatry, Munich, Germany (supervisor: D. Auer)
Doctoral student, NMR study group, Max Planck Institute for Psychiatry, Munich, Germany (supervisors: D. Auer, R. Landgraf)
Secretary of intresa
Coordinator EU Horizon 2020 project DynaMORE (Dynamic MOdelling of REsilience)
Founding spokesperson of intresa (International Resilience Alliance)
Initiator and main organizer of International Symposium on Resilience Research
DFG Emmy Noether Research Group
EU Marie Curie Individual Fellowship for postdoctoral studies
Stipend of Medizinstiftung, University of Marburg for diploma studies at Ecole Normale Supérieure, Paris, France
Professor Dr. Raffael Kalisch has been University Professor for Human Neuroimaging at the University Medical Center Mainz since 2012 and working group leader at the Leibniz Institute for Resilience Research since 2020. He has not received any personal fees for statements from pharmaceutical companies or medical device manufacturers since 2018. Between 2019-2021, Prof. Kalisch has performed consulting activities, such as grant application reviews and grant program designs, for JoyVentures, Herzlia, in Israel. From the non-profit Boehringer Ingelheim Foundation, Prof. Kalisch, together with other LIR scientists, received research funding for 2017-2020 to establish the Leibniz Institute for Resilience Research. He has been a board member and secretary in the International Resilience Alliance (intresa e.V.) since 2018.
Expert fees
2020
- Interdisciplinary Center for Clinical Research, RWTH Aachen University, Germany
- Joy Ventures, Herzliya, Israel
Speaker fees
2023
- Professional Association of German Psychologists, Saarland Regional Group
- Besser-Siegmund-Institut GmbH, Hamburg
2022
- Hessian State Office for Technology Training, Groß-Gerau
- Interdisciplinary Center for Clinical Research, RWTH Aachen University
2021
- Institute for Self-Management and Motivation Zurich
- Protestant City Academy Munich
2020
- Academy of Foreign Service, German Federal Foreign Office
- Psychosomatic Research Colloquium, University of Ulm, Germany
- Nantesbuch Foundation gGmbH
Ahrens KF, Schenk C, Kollmann B, Puhlmann LMC, Neumann RJ, Schäfer SK, Reis D, Basten U, Weichert D, Fiebach CJ, Lutz B, Wessa M, Repple J, Lieb K, Tüscher O, Reif A, Kalisch R, Plichta MM. Resilience to major life events: Advancing trajectory modeling and resilience factor identification by controlling for background stressor exposure. Am Psychol. 2024 Nov;79(8):1076-1091. doi: 10.1037/amp0001315. PMID: 39531708.
>> Link to PubmedKalisch R, Russo SJ, Müller MB. Neurobiology and systems biology of stress resilience. Physiol Rev. 2024 Jul 1;104(3):1205-1263. doi: 10.1152/physrev.00042.2023. Epub 2024 Mar 14. PMID: 38483288; PMCID: PMC11381009.
>> Link to PubmedAndres E, Chuan-Peng H, Gerlicher AMV, Meyer B, Tüscher O, Kalisch R. Replication study on the role of dopamine-dependent prefrontal reactivations in human extinction memory retrieval. Nat Commun. 2024 Mar 27;15(1):2699. doi: 10.1038/s41467-024-46936-y. PMID: 38538636; PMCID: PMC10973457.
>> Link to PubmedPetri-Romão P, Engen H, Rupanova A, Puhlmann L, Zerban M, Neumann RJ, Malyshau A, Ahrens KF, Schick A, Kollmann B, Wessa M, Walker H, Plichta MM, Reif A, Chmitorz A, Tuescher O, Basten U, Kalisch R. Self-report assessment of Positive Appraisal Style (PAS): Development of a process-focused and a content-focused questionnaire for use in mental health and resilience research. PLoS One. 2024 Feb 2;19(2):e0295562. doi: 10.1371/journal.pone.0295562. PMID: 38306328; PMCID: PMC10836662.
>> Link to PubmedAyash S, Lingner T, Ramisch A, Ryu S, Kalisch R, Schmitt U, Müller MB. Fear circuit-based neurobehavioral signatures mirror resilience to chronic social stress in mouse. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2205576120. doi: 10.1073/pnas.2205576120. Epub 2023 Apr 17. PMID: 37068238; PMCID: PMC10151471.
>> Link to PubmedKöber G, Pooseh S, Engen H, Chmitorz A, Kampa M, Schick A, Sebastian A, Tüscher O, Wessa M, Yuen KSL, Walter H, Kalisch R, Timmer J, Binder H (2022). Individualizing deep dynamic models for psychological resilience data. Sci Rep. 2022 May 16;12(1):8061. doi: 10.1038/s41598-022-11650-6
>> Link to PubmedSchäfer SK, Kunzler AM, Kalisch R, Tüscher O, Lieb K (2022). Trajectories of resilience and mental distress to global major disruptions. Trends Cogn Sci. 2022 Oct 24:S1364-6613(22)00238-8. doi: 10.1016/j.tics.2022.09.017. Online ahead of print
>> Link to PubmedKalisch R, Köber G, Binder H, Ahrens KF, Basten U, Chmitorz A, Choi KW, Fiebach CJ, Goldbach N, Neumann RJ, Kampa M, Kollmann B, Lieb K, Plichta MM, Reif A, Schick A, Sebastian A, Walter H, Wessa M, Yuen KSL, Tüscher O, Engen H (2021). The Frequent Stressor and Mental Health Monitoring-Paradigm: A Proposal for the Operationalization and Measurement of Resilience and the Identification of Resilience Processes in Longitudinal Observational Studies. Front Psychol. 12:710493.
>> Link to PubmedKöber G, Kalisch R, Puhlmann L, Chmitorz A, Schick A, Binder H (2021) Deep learning and differential equations for modeling changes in individual-level latent dynamics between observation periods. Biometrical Journal. 52. In press
>> Link to PubmedVeer et al (2021) Psycho-social factors associated with mental resilience in the Corona lockdown. Transl Psychiatry 11:67.
>> Link to PubmedUngar M et al (2021) Multisystemic Resilience: Adaptation and Transformation in Contexts of Change
>> Link to articleChmitorz A, Kurth K, Mey LK, Wenzel M, Lieb K, Tüscher O, Kubiak T, Kalisch R (2020). Assessment of microstressors in adults: Questionnaire development and ecological validation of the Mainz Inventory of Microstressors. JMIR Ment Health 7(2):e14566.
>> Link to PubmedKampa M, Schick A, Sebastian A, Wessa M, Tüscher O, Kalisch R, Yuen K (2020). Replication of fMRI group activations in the neuroimaging battery for the Mainz Resilience Project (MARP). Neuroimage 204:116223.
>> Link to PubmedKalisch R, Gerlicher AMV, Duvarci S (2019) A Dopaminergic Basis for Fear Extinction. Trends Cogn Sci 23:274-7.
>> Link to PubmedGerlicher AMV, Tüscher O, Kalisch R. Dopamine-dependent prefrontal reactivations explain long-term benefit of fear extinction. Nat Commun. 2018 Oct 16;9(1):4294. doi: 10.1038/s41467-018-06785-y. Erratum in: Nat Commun. 2019 Jan 23;10(1):471. doi: 10.1038/s41467-019-08399-4. PMID: 30327462; PMCID: PMC6191435.
>> Link to PubmedSalinas-Hernández XI, Vogel P, Betz S, Kalisch R, Sigurdsson T, Duvarci S. Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes. Elife. 2018 Nov 13;7:e38818. doi: 10.7554/eLife.38818. PMID: 30421719; PMCID: PMC6257816.
>> Link to PubmedKalisch R, Baker DG, Basten U, Boks MP, Bonanno GA, Brummelman E, Chmitorz A, Fernàndez G, Fiebach CJ, Galatzer-Levy I, Geuze E, Groppa S, Helmreich I, Hendler T, Hermans EJ, Jovanovic T, Kubiak T, Lieb K, Lutz B, Müller MB, Murray RJ, Nievergelt CM, Reif A, Roelofs K, Rutten BPF, Sander D, Schick A, Tüscher O, Van Diest I, van Harmelen AL, Veer IM, Vermetten E, Vinkers CH, Wager TD, Walter H, Wessa M, Wibral M, Kleim B (2017) The resilience framework as a strategy to combat stress-related disorders. Nat Hum Behav 1:784−790.
>> Link to PubmedKalisch R, Müller MB, Tüscher O (2015) A conceptual framework for the neurobiological study of resilience. Behav Brain Sci 27:1−79
>> Link to PubmedHaaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K, Singewald N, Pape HC, Morellini F*, Kalisch R* (2013) Single dose of L-DOPA makes extinction memories context-independent and prevents the return of fear. Proc Natl Acad Sci USA 110:E2428−E2436. *equal contribution
>> Link to PubmedRaczka KA, Mechias ML, Gartmann N, Reif A, Deckert J, Pessiglione M, Kalisch R. Empirical support for an involvement of the mesostriatal dopamine system in human fear extinction. Transl Psychiatry. 2011 Jun 7;1(6):e12. doi: 10.1038/tp.2011.10. PMID: 22832428; PMCID: PMC3309464.
>> Link to PubmedEtkin A, Egner T, Kalisch R (2011) Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 15:85−93.
>> Link to PubmedRaczka KA, Gartmann N, Mechias ML, Reif A, Buchel C, Deckert J, Kalisch R (2010) A neuropeptide S receptor variant associated with overinterpretation of fear reactions: a potential neurogenetic basis for catastrophizing. Mol Psychiatry 15:1067−1074. Corrigendum: 17:468.
>> Link to PubmedKalisch R (2009) The functional neuroanatomy of reappraisal: time matters. Neurosci Biobehav Rev 33:1215-26.
>> Link to PubmedPessiglione M, Schmidt L, Draganski B, Kalisch R, Lau H, Dolan RJ, Frith CD (2007) How the brain translates money into force: a neuroimaging study of subliminal motivation. Science 316:904−906.
>> Link to Pubmed